目的:探讨大切口无缝线白内障囊外摘除术(SLIMCE)后泪膜情况。方法:行SLIMCE术眼68例,分别于术前及术后7,14,30,60,90d行症状、泪膜破裂时间(BUT)、基础泪液分泌试验(SⅠt)、角膜荧光素染色(FL)检测。运用结膜印迹细胞学及显微图象分析系统对SLIMCE术区结膜杯状细胞进行记数分析。结果:90d内术眼不适患者较术前增加(5-27,23,19,16,13;2-16,14,8,6,3),术后14d内SⅠt增加(10.1±4.5;15.0±4.7,13.8±5.7),30d内BUT缩短(10.3±2.2;5.5±2.3,7.0±2.4,7.9±2.2),FL增高(0-17,9,5;0-8,3,1),与术前相比有统计学差异(P<0.05)。结论:SLIMCE术后会影响泪膜稳定性。

AIM:To investigate the alterations of tear film after sutureless large incision manual cataract extraction (SLIMCE). METHODS:Sixty-eight SLIMCE operation eyes were studied with slit-limp microscope,break-up time (BUT),SchirmmerⅠtest (SⅠt),and fluorescence(FL) to observe the alterations of tear film at different time points in postoperation. Impression cytology and microphoto-analyses technique were also applied to observe the goblet cells at different time points postoperation(7,14,30,60,90 days). RESULTS:Subjective complaint of dry eye within 90 days after the operations were significantly increased compare with preoperations(5-27,23,19,16,13; 2-16,14,8,6,3). The schirmmer Ⅰ test were greatly increased in 14 days postoperation(10.1±4.5;15.0±4.7,13.8±5.7),the mean scores of fluorescence increased (0-17,9,5;0-8,3,1) and the mean break-up time decreased in 30 days post-operation(10.3±2.2;5.5±2.3,7.0±2.4,7.9±2.2) (P<0.05). CONCLUSION:SLIMCE operation have effect on the stability of tear film.

R779.66