目的:探讨LASEK术中应用丝裂霉素C于高度近视患者中预防haze的可行性。方法:选取24例48眼高度近视患者,随机分为2组,其中11例22眼为对照组,13例26眼为试验组,对照组进行常规LASEK术,试验组在LASEK术中激光切削完毕未回复上皮瓣前使用浸泡0.2g/L丝裂霉素C棉片覆盖于激光切削区约12s,冲洗后回复上皮瓣并置入隐形眼镜5d。随访观察术后视力、角膜haze情况等6mo。结果:术后6wk试验组与对照组haze无统计学意义,术后3,6mo试验组haze轻于对照组(P<0.05)。结论:丝裂霉素C在LASEK术中应用于高度近视患者能有效预防haze的形成。

AIM:To evaluate the feasibility of mitomycin C (MMC) in preventing haze in LASEK surgery of high myopia.METHODS:Twenty-four high myopia patients(48 eyes) were randomly divided into two groups,one group included 11 patients(22 eyes) which operated LASEK surgery as usual and the other group(26 eyes) received 0.2g/L MMC sponge in the operation,and the time lasted for 12 seconds. After operation and the cornea was covered with gas-permeable soft contact lens. All of the patients were followed up,including vision and haze etc. for half a year. RESULTS:There was no difference of the haze between the two groups 6 weeks after the operation. 3 months,6 months after operation the haze in MMC group was lighter than that of the control group (P<0.05). CONCLUSION:MMC seems to be effective to prevent the haze in the surgery of LASEK of high myopia.

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