目的:探讨舌下含服粉尘螨滴剂脱敏治疗季节性及常年性过敏性结膜炎的治疗效果。方法:选择80例160眼对尘螨过敏的季节性及常年性过敏性结膜炎患者,随机分为对照组与实验组,对照组发作期口服抗组胺药,维生素C钙片,外滴色干酸钠眼药水及妥布霉素地塞米松眼药水,实验组在对照组基础上加舌下含服粉尘螨滴剂脱敏治疗。结果:对照组显效8例(20.0%),有效21例(52.5%),无效11例(27.5%),总有效率72.5%。实验组显效21例(52.5%),有效16例(40.0%),无效3例(7.50%),总有效率92.5%,两组比较有统计学意义(P<0.05)。不良反应5例,均为局部症状,如口、舌或唇的轻微肿胀,无全身不良反应发生。结论:舌下含服粉尘螨滴剂脱敏治疗对过敏性结膜炎具有明显疗效,且患者使用方便,不良反应发生率低。

AIM:To survey the effect of sublingual immunotherapy in allergic conjunctivitis. METHODS:Eighty patients of seasonal and perennial allergic conjunctivitis were divided into two groups,one group was prescribed cetirizine and vitamin C for them to take orally,sodium cromoglicate or dexamethasone/chloromycetin gutta ad hibeo,meanwhile the other group was treated respectively with sublingual immunotherapy. Record the symptom pre & post immunotherapy and side-effects,and run statistical analysis to the results. RESULTS:The total effective rate in experimental group was 92.5%,while in control group was 72.5%,There were significant differences between pre & post therapy in both the two groups(P<0.05). There was no systemic adverse reactions.CONCLUSION:The sublingual immunotherapy had obvious cure effect to the seasonal and perennial allergic conjunctivitis.

R777.3