目的:观察虹膜定位联合波前像差引导的EPI-LASIK手术治疗高度近视的效果。方法:将自愿接受手术的高度近视患者54例108眼分为两组:一组29例58眼接受虹膜定位联合波前引导的EPI-LASIK术(波前组);另一组25例50眼接受常规EPI-LASIK术(常规组);术后随访期间进行裸眼视力、屈光度、高阶像差、主观感觉做以分析。结果:术后6mo时,两者比较,裸眼视力差异无统计学意义意义(P>0.05)。最佳矫正视力提高两行以上的两组患者比较差异有显著统计学意义(P<0.01);屈光度存在统计学差异;高阶像差有显著统计学差异(P<0.01);主观感觉的眩光症状比较,有统计学意义(P<0.05)。结论:虹膜定位联合波前引导的EPI-LASIK矫正高度近视在有些方面优于常规的EPI-LASIK。

AIM:To observe the clinical effect of wavefront aberration and iris location guided epipolis laser in situ keratomileusis( EPI-LASIK )for high myopia.·METHODS:Fifty-four patients(108 eyes)with corneal high myopia were randomly divided into wavefront aberration and iris location guided EPI-LASIK group of twenty-nine patients (58 eyes)and conventional EPI-LASIK group of twenty-five patients (50 eyes).The uncorrected visual acuity(UCVA),refractions,vision quality and high-order aberration value were analyzed during the postoperative follow-up.·RESULTS:At 6th month postoperatively,there was no significant diference of the UCVA (P>0.05)between two groups;The postoperative UCVA of all eyes was satisfied,gained over 2 line of best-corrected visual acuity(BCVA) in wavefront guided group and gained over 2 line of BCVA in conventional group,there was significant diference between the two group(P<0.01);The postoperative refractions,vision quality was statistically different between the conventional group and wavefront guided group(P<0.05);there was significant difference in the postoperative high-order aberration between the two groups(P<0.01).·CONCLUSION:The wavefront aberration and iris location guided EPI-LASIK in some field is better than conventional EPI-LASIK for the treatment of high myopia.·

R779.63