正常人与原发性开角型青光眼和闭角型青光眼视盘萎缩弧β区发生率的比较
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Comparison on the prevalence of peripapillary atrophyβzone in normal persons and primary open angle glaucoma and primary angle-closure glaucoma
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    摘要:

    目的:比较正常人和青光眼(原发性开角型青光眼(primary open angle glaucoma,POAG)、闭角型青光眼(primary angle-closure glaucoma,PACG))间视盘萎缩弧β区发生率的差异。方法:选择年龄、屈光度数相匹配的正常人135例135眼、POAG58例101眼、PACG50例81眼。利用海德堡眼底照相机采集受试者30°眼底彩色照片,并用计算机图像处理软件测量青光眼患者垂直杯盘比,利用卡方检验分析不同程度青光眼损伤的患者眼底β区发生率与垂直杯盘比的关系。结果:正常人、POAG和PACGβ区发生率分别为23.0%,69.3%和49.4%(χ2=51.3,P=0.000);POAG的β区发生率高于PACG(χ2=7.5,P=0.005)。三组人群β区最多见于水平颞侧象限,鼻侧象限最少(χ2=19.4,P=0.000;χ2=50.3,P=0.000;χ2=11.7,P=0.009);POAG组中,视神经损伤较重组的β区发生率明显高于较轻组(χ2=14.0,P=0.000);PACG组中,视神经损伤较重组β区发生率与较轻组无明显差异(χ2=0.6,P=0.287)。结论:POAG和PACGβ区发生率高于正常人,POAGβ区发生率高于PACG。视神经损伤较重组POAG眼相对于较轻组更易发生β区。

    Abstract:

    RESULTS: Among the entire Nd∶YAG laser sufferers 14 days later, in the center of the corneal endothelium, the decrease of the cell density(CD) revealed statistically significant difference (P<0.05). After the treatment of peripheral iridectomy 14 days later, in the center of the corneal endothelium, the decrease of the CD revealed statistically significant difference (P<0.05). 7 days later, in the periphery of the corneal endothelium, average cell area,minimum cell area, CD and percentage of hexagonal endothelium(6A) were analyzed with statistically significant difference (P<0.05). There was no significant correlation between pre- and postoperative central and 6 oclock periphery of corneal endothelium in central serous chorioretinopathy(CSC).

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王涵,朱奇,张劲松.正常人与原发性开角型青光眼和闭角型青光眼视盘萎缩弧β区发生率的比较.国际眼科杂志, 2010,10(3):469-471.

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