·AIM:To observe the clinical effect of using mitomycin C(MMC)during surgical treatment of epithelial ingrowth after laser in situ keratomileusis(LASIK).·METHODS:MMC 0.2g/L was applied in surgical treatment of epithelial ingrowth after LASIK on 31 patients(31 eyes).The uncorrected visual acuity and the recovery of corneal flap were observed after surgery.·RESULTS:The uncorrected visual acuity increased after surgery(P<0.05)and was 0.82±0.19 6 months posto-peratively.Majority of corneal flaps recovered well.Fringe of the flap melted in 4 eyes,but central visual acuity had no effect.·CONCLUSION:Excellent outcome was found in the surgical treatment of epithelial ingrowth after LASIK by using 0.2g/L MMC.·