·AIM:To evaluate the fundus fluorescein angiography(FFA)for the diagnosis of age related macular degene-ration(AMD).·METHODS:AMD patients were examined by FFA using Topocon TRC-NW7SF fundus camera and analysed in combination with other clinical examinations.·RESULTS:In total of 62 eyes in 40 AMD patients,49 eyes(79%)were diagnosed as atrophic type,13 eyes(21%)exudative type.The atrophic type showed spots or mottled shape in fluorescence transmission,and no fluorescein leakage was found.In the early stage of exudative type,choroidal neovascularization(CNV)could be seen,and in the later stage,there was a lot of fluorescein leakage;the blocked fluorescence was observed if hemorrhage formed around.·CONCLUSION:The application of FFA helps the early diagnosis of AMD and points out the area and location of CNV.·