目的:分析以视神经炎(optic neuritis,ON)为首诊的多发性硬化(multiple sclerosis,MS)21例,提高对ON与MS的认识,评价大剂量甲强龙冲击治疗效果。方法:回顾性分析我院2004-04/2008-04收治的以ON为首诊的MS21例的临床表现、诊断及治疗。结果:患者4例符合Poser诊断标准,17例行MRI后确诊;通过给以大剂量甲强龙冲击治疗,15例(71%)患者视力改善。结论:对于首发视力障碍就诊于眼科、诊断为视神经炎的患者,应常规行MRI检查以除外MS,大剂量甲强龙冲击治疗是MS首选方式。

·AIM:To devote much attention to the study on diagnosis and treatment of optic neuritis(ON)and multiple sclerosis(MS).·METHODS:The 21 ON among the patients of MS who were admitted to eye center of the affiliated hospital of Mudanjiang medical university from 2004 to 2008 were retrospectively analyzed,clinical symptom,diagnosis and therapy of MS with first-diagnosis of ON were investigated.·RESULTS:According to Poser and MRI criteria of diagnosis,21 cases were identified as MS.Through treatment of a large dose of methylprednisolone,the visual acuity of 15 cases(71%)was improved.·CONCLUSION:It is necessary for patients with optic neuritis to do conventional MRI to exclude MS.A large dose of methylprednisolone is the first choice.·

R744.51