AIM:To observe the morphology of corneal endotheliitis by confocal microscope.METHODS: Confoscan 4.0 (made in Japan) was used to scan the 24 cases 24 eyes suffered from corneal endotheliitis and the image of every corneal sheet was recorded.RESULTS: Opacitas were found in anterior stroma.In deeper stroma, stroma cell was disorder and high glisten structure and DM reductus were found. High glisten structure were found before corneal endothelium which suggested that pleomorphism transform in corneal endothelium. There were corneal epithelium cell degeneration in 4 eyes.CONCLUSION: By confocal microscope we can observe the morphology of every corneal sheet as well as histopathologic slide. The morphological characteristic of corneal endotheliitis is that the deeper stroma and endothelium are damaged. Confocal microscope has certain reference value for cormeal endothelitis.