AIM:To observe the therapeutic effect of kudiezi on anterior ischmic optic neuropathy(AION).METHODS:In 32 patients 32 eyes who were diagnosed as with AION,16 patients 16 eyes underwent intravenous drip with kudiezi 20mL (treatment group),and the other 16 patients 16 eyes underwent intravenous drip with dansen 20mL (control group) with the period of treatment of 15 days.The changes of visual acuity and ocular fundus of the patients after injection were recorded,and the visual field was checked before and after the treatment.RESULTS:The visual acuity was better in treatment group than that in control group with significant difference (P<0.01).At the 3rd,7th and 15th day after treatment,the visual acuity was better in treatment group than that in control group with significant difference(P<0.01;P<0.05;P<0.01).In treatment group,the visual field improved in 14 eyes (87.50%)and of remained unchanged in 2 eyes (12.50%).In control group,the visual field improved in 7 eyes(43.75%)and remained unchanged in 9 eyes (56.25%).There was significant difference between the two groups (P<0.01).CONCLUSION:Kudiezi is efficacious in treatment of AION.