AIM:Therapeutic methods of XL-radiofrequency abla-tion skin apparatus (invented by department of Phy-siotherapy,Chinese PLA General Hospital) in eradicating xanthelasma palpebrarum are studied and their clinical effects are investigated.METHODS:XL-radiofrequency ablation skin apparatus was performed on 40 cases 73 lesions of xanthelasma palpebrarum with the length of 3-15mm and width of 3-10mm in an area of 6-150 (average 44±34)mm2 by separat-ing layer and ablation removing methods.The postopera-tive follow-up durations ranged from 1 to 3 years.RESULTS:In 40 patients with 73 lesions,35 cases 67 lesions were cured successfully by once and 4 cases 6 lesions by twice with well healing,no-scarring with cure in 39 cases and marked result in 1 case.1 case 2 lesions had a recurrence in postoperation of 7 months,2 cases 2 lesions had a slight hypopigmentation.The protective crust over lesion was formed next day and fall off half month postoperation.Local erythemia in several cases occurred after the crust fall off and disappeared during 6 to 10 months.XL-radiofrequency ablation skin apparatus offered several advantages,such as easy operation,high accuracy,clear visible field under the operative magnifier,no bleeding,shorter operation time,no smog,little pain,one-off ablation electrode during the procedure,slight inflammation reaction,no infection,no antibiotics follow-ing operation,no visible scarring and lower recurrence after healing.CONCLUSION:The efficacy of XL-radiofrequency abla-tion skin apparatus is significantly more evident and safe in eradicating xanthelasma palpebrarum.