Abstract:AIM:To observe the Bausch & Lomb Zyoptix individualized LASIK of cornea saving treatment for myopia,and analyze postoperative changes in higher-order aberrations.METHODS:Thirty-two patients 64 eyes with thin cornea myopia unsuitable for conventional LASIK surgery under-went the Zyoptix LASIK surgery.The degree of the cornea saved,the recovery of vision at 1 year and 6mm pupil diameters changes in higher-order aberrations were analyzed.RESULTS:The average saved corneal tissue was 29.27μm (21.36%);1 year after operation,uncorrected visual acuity was 0.93±0.24,visual acuity was signifi-cantly improved compared with that of preoperative (P<0.01),and similar to the preoperative best-corrected visual acuity (0.96±0.09);81% of cases have the better postoperative visual acuity than the preoperative best-corrected visual acuity,visual acuity was improved in all cases.At 6mm pupil diameter,the overall higher-order aberrations,third order coma and the fourth order spherical aberration were increased 1.76 times,2.10 times,3.90 times compared with that of the preoperative,similar to conventional LASIK surgery.CONCLUSION:Zyoptix individualized LASIK of cornea saving can save 20%-25% of the corneal tissue,expand the treatment scope of myopia,and have a good safety,efficacy and predictability in clinic.