AIM:To observe the effect of treatment of fungal keratitis with local debridement combined with 50g/L anerdian type 3 disinfectant dilution used in conjunctival sac and medication. ·METHODS:Sixty-one patients 61 eyes were treated with local debridement combined with 50g/L anerdian type 3 disinfectant dilution used in conjunctival sac and medication and the effects were observed. ·RESULTS:The cure rate was as the follows:of the mild 100%,of the moderate 78%,of the serious 27%. ·CONCLUSION:The treatment result of local debride-ment combined with 50g/L anerdian type 3 disinfectant dilution used in conjunctival sac and medication is better for the mild and the moderate,yet not effective for the serious cases.