AIM:To evaluate the safety.complication and effect of Ho:YAG laser thermokeratoplasty(LTK)for the treatment of mild hyperopia without astigmatism. METHODS:In the thesis,Ho:YAG LTK was used to treat mild hyperopia.18 eyes of 12 patients(aged>45 years) were treated and the energy density was 65J/cm~2. The average follow-up period was 2 years. RESULTS:The mean age of patients was 55.25±10.12 years(range:45-65 years).The preoperative hyperopic mean spherical equivalent refraction was + 1.30±0.58D (range:+ 0.50D to +2.25D).The preoperative uncorrected visual acuity(UCVA) was 0.44±0.23.All refractive error were corrected with no regression one month postoperatively.Only four eyes regressed + 0.25D three months postoperation.Six months later,the percentage of the residual refractive error less than±0.50D was 83% and less than±1.00D 89%.There was good coincidence ratio between the corrected refraction diopter and the attemped refraction diopter.And then there was a tendency of refractive regression.Two years later,the regression began to slow down.The best visual acuity appeared two weeks after operation,and then naked eye visual acuity began to regress.The preoperative UCVA equaled or more than 1.0 was 0.Three months postoperatively,the naked eye visual acuity increased very evidently.Three months postoperatively,UCVA equaled or more than 1.0 went to 78%(14 eyes).Two years later,UCVA equaled or more than 1.0 was 56%(10 eyes). CONCLUSION:Ho:YAG LTK is effective to treat simple low hyperopia.From clinical observation,it is evident that LTK operation is simple,safe,fast,and effective without short-term complication.LTK seems to be one of the promising procedures to treat mild hyperopia.We still need to observe its long time refraction stability.