AIM:To investigate the therapeutic effects of preventive laser photocoagulation for myopia patients with peripheral retinal degeneration or holes before LASIK operation. METHODS:Before operation,the fundus was examined with direct and indirect ophthalmoscope and three-mirror contact lens.The 532nm laser photocoagulation was performed in order to strengthen the retina with severe peripheral degeneration. RESULTS:Peripheral fundus abnormalities and holes both increased with increased refraction diopter.The abnormalities were usually in the temporal fundus. Patients were followed up for 10 months,and no rhegmatogenous retinal detachment was found. CONCLUSION:It is necessary to know the retinopathy before operation.Preventive 532nm laser photocoagulation for moderate and high myopia patients,who were confirmed to have peripheral retinal degeneration or retinal holes before LASIK operation,is very necessary.