AIM:To investigate the effects of compound anisodine and Sutaisheng for late optic nerve contusion eyes with no light perception METHODS:The pathogenesis characteristics and clinic treatment of compound anisodine and sutaisheng on late optic nerve contusion eyes with no light perception was analyzed retrospectively in 11 cases.According the result, these eyes were divided into two groups:effective-group and negative-group. RESULTS:The visual acuity of 4 was cases improved. The outcome of visual acuity was better in patients with the following conditions:the longer time of eyes turning into no light perception after trauma and presence of VEP. CONCLUSION:Late optic nerve contusion eyes with no light perception,which has the longer time of eyes turning into no light perception after trauma and presence of VEP, need active treatment.Anisodine and sutaisheng was the effective treatment for these cases.