·AIM:To evaluate the effect of the preventive retinal laser photocoagulation on the following eye in patients with peripheral retinal degeneration or associated with dry holes after retinal detachment operation.·METHODS:Patients who met the above conditions were evaluated for the presence of vitreoretinal changes using Goldman three-mirror contact len or indirect ophthalmoscopy.192 cases in contralateral eyes with peripheral retinal degeneration(lattice degeneration,snail track degeneration,cystic degeneration,etc.)or associated with dry holes received the preventive retinal laser photocoagulation.·RESULTS:The areas of peripheral retinal degeneration or dry holes in the following eyes of 192 patients who received the preventive retinal laser photocoagulation were closed well,and the pigment spots were sharp.All cases who had been treated by laser photocoagulation were followed up for 6-18 months.No retinal detachment was found.·CONCLUSION:The preventive retinal laser photocoagulation on peripheral retinal degeneration or associated with dry holes is effective to prevent the occurrence of retinal detachment.·