·AIM:To observe the clinical effects of Augentropfen Stulln Mono eye-drops for asthenopia after laser in situ keratomileusis(LASIK).·METHODS:Totally 200 patients 400 eyes with earlier period asthenopia after LASIK were divided into treatment and control groups,in addition to conventional postoperative medication:the treatment group were added with Augentropfen Stulln Mono eye-drops(n=100),the control groups were added with Celluvisc eye-drops(n=100).On postoperative week 1,2,4,signs and symptoms of asthenopia were evaluated and drug adverse reaction were observed.·RESULTS:Asthenopia of all the patients were released gradually with the extension of operative time.One week and two weeks after surgery,the treatment groups’ asthenopia score was lower than the control groups’,and there were significant differences(P<0.05);four week after surgery the asthenopia score of two groups were 1.06±0.65 and 1.21±0.83,the difference was not significant(P>0.05).·CONCLUSION:Augentropfen Stulln Mono eye-drops are effective and safe for earlier period asthenopia after LASIK.·