七叶洋地黄双苷治疗LASIK术后视疲劳的临床疗效观察
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R779.63

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Clinical effects of Augentropfen Stulln Mono eye-drops for asthenopia after laser in situ keratomileusis
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    摘要:

    目的:评价七叶洋地黄双苷滴眼液治疗近视患者准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)后视疲劳的临床疗效。方法:对200例400眼近视患者行LASIK手术,随机分成两组。100例为试验组应用七叶洋地黄双苷滴眼液,另100例为对照组应用潇莱威滴眼液。分别于手术前、用药后1,2,4wk评估患者术后视疲劳的症状和体征,同时观察药物不良反应。结果:随着术后时间的延长,试验组和对照组近视患者视疲劳症状逐渐缓解,在术后1,2wk时,试验组的视疲劳评分低于对照组,两组差异有统计学意义(t=3.160,P=0.001;t=2.727,P=0.0025);术后4wk时,两组的差异无统计学意义(t=1.423,P=0.10)。结论:随着观察时间的延长,LASIK术后患者视疲劳症状可逐渐得到恢复和改善,七叶洋地黄双苷滴眼液对改善LASIK术后早期视疲劳症状有效。

    Abstract:

    ·AIM:To observe the clinical effects of Augentropfen Stulln Mono eye-drops for asthenopia after laser in situ keratomileusis(LASIK).·METHODS:Totally 200 patients 400 eyes with earlier period asthenopia after LASIK were divided into treatment and control groups,in addition to conventional postoperative medication:the treatment group were added with Augentropfen Stulln Mono eye-drops(n=100),the control groups were added with Celluvisc eye-drops(n=100).On postoperative week 1,2,4,signs and symptoms of asthenopia were evaluated and drug adverse reaction were observed.·RESULTS:Asthenopia of all the patients were released gradually with the extension of operative time.One week and two weeks after surgery,the treatment groups’ asthenopia score was lower than the control groups’,and there were significant differences(P<0.05);four week after surgery the asthenopia score of two groups were 1.06±0.65 and 1.21±0.83,the difference was not significant(P>0.05).·CONCLUSION:Augentropfen Stulln Mono eye-drops are effective and safe for earlier period asthenopia after LASIK.·

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何芳,宋伟琼,李国桥,等.七叶洋地黄双苷治疗LASIK术后视疲劳的临床疗效观察.国际眼科杂志, 2010,10(11):2189-2190.

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