AIM:To determine the impact of wearing several kinds of spectacles on progression of 50 myopia cases with esophoria.METHODS:Fifty myopia with esophoria were collected from 2004-2009,and whose refraction data and medical records were analyzed yearly.Wearing spectacles were ordinary glasses,reading glasses(reducing-1.50D),multifocal lens(MC),and reading additional lens,respectively.The refraction change of the four groups were analyzed by paired sample t-test.RESULTS:There were 50 patients,aged 9 to 17 years(12.04±2.53),26 males and 24 females.MC was better than ordinary glasses in controlling the increase of degree of sphere in myopia(P<0.01).Reading additional lens were more effective in controlling the increase of degree of sphere and cylinder than MC(P<0.01).The degree of cylinder could increase and the best-corrected visual acuity could decrease because of long-time wearing of MC,while wearing reading additional lens could improve the best-corrected visual acuity.CONCLUSION:Myopia progression is faster in patients wearing ordinary glasses than reading glasses(reducing-1.50D)and MC.Myopia progression will slow down wearing reading additional lens.