AIM:To investigate the therapeutic effect of Ahmed glaucoma valve implantation with mitomycin C combined with retinal photocoagulation in treatment of neovascular glaucoma.METHODS:Twenty-six eyes with neovascular glaucoma were underwent the implantation of glaucoma valve combined with panretinal photocoagulation.RESULTS:Follow-up 12 months,the success rate was 61.54%.the average intraocular pressure decreased from 49.78±14.17mmHg preoperatively to 18.45±8.91mmHg postoperatively.In the postoperative ultimate check-up,visual acuity of 14 cases were improved(53.85%),12 cases had no change,No case was decreased and impairmented.The new vessels of the iris disappeared in 21 eyes.The important complications such as shallow anterior chamber was 6 in eyes(23.08%),hyphema 3 eyes(11.54%),tube occlusion 2 eyes(7.69%),fibrosis around Ahmed valve 1 eye(3.85%).CONCLUSION:Ahmed glaucoma valve implantation combined with panretinal photocoagulation in treatment of neovascular glaucoma can not only decreased intraocular pressure timely but also increased visual acuity.It is a safe and effective approach to those patients with neovascular glaucoma.