AIM:To evaluate the improvement outcomes of visual acuity of puerarin combined with mecobalamin and fuming tablet in pituitary adenoma after operation.METHODS:We divided 32 cases 48 eyes into two groups at random,chose surgery alone as control group and drug treatment of puerarin combined with mecobalamin and fuming tablet after operation as experimental group.RESULTS:The improvement of visual acuity after operation in the experimental group was better than that in the control group,there was statistically significant difference(P<0.05).CONCLUSION:Applying puerarin combined with mec-obalamin and fuming tablet in pituitary adenoma after operation can acquire satisfactory effect in the improvement of visual acuity.