Abstract:·AIM:To compare the fornix-based conjunctival flap and corneal limbus-based conjunctival flap with auxiliary eyeball massage therapy on the formation of functional filtering bleb after compound trabeculectomy in glaucoma.METHODS:A total of 51 patients(61 eyes)with primary glaucoma and combined trabeculectomy were randomly divided into two groups:A group of 26 patients(31 eyes)were of limbus-based conjunctival flap;B group of 25 patients(30 eyes)of fornix-based conjunctival flap.Postoperative Intraocular pressure,filtering bleb and anterior chamber depth were observed in two groups,and timely eyeball massage therapy was applied accordingly.All cases were observed for 6 months.RESULTS:Intraocular pressure lowering effect of two conjunctival flap combined trabeculectomy was both significant(P<0.01);functional bleb formation rate was no statistically significant difference(P>0.05);passive leakage of filtering bleb was more in B group than that of A group during eyeball massage’ promotion of filtering bleb formation at early postoperative stage.CONCLUSION:The two conjunctival flap combined trabeculectomy for glaucoma have the same good results.Eyeball massage can promote the formation of functional bleb.Eyeball massage therapy after limbus-based conjunctival flap compound trabeculectomy has less passive filtering bleb leakage.