·AIM:To observe the image characteristics of infrared ray(IR)and autofluorescence(AF)in central serous chorioretinopathy(CSC).METHODS:Totally 80 eyes of 76 CSC patients were examined the infrared photography of ocular fundus,autofluorescence photography of ocular fundus,fundus fluorescein angiography(FFA)using IR imaging mode and FA imaging mode of Heidelberg Spectralis HRA.RESULTS:In 80 eyes,the IR image of CSC focus contained dark macular edema area,clear periphery in the macula layer detachment area,white spot-like focus existed specifically in the leaking area.The AF image of CSC focus showed patterns characterized as weak plate-like AF in the macular edema area(18 eyes of 18 patients,22.50%),weak AF with strong spot-like AF in the macular edema area(13 eyes of 13 patients,16.25%),weak AF with strong lamellar AF in the macular edema area(11 eyes of 11 patients,13.75%),strong AF circle in the periphery of macula layer detachment area(3 eyes of 3 patients,3.75%),weak AF combined with strong spot-like AF(21 eyes of 19 patients,26.25%),local densed strong AF and weak AF at the posterior pole(3 eyes of 3 patients,3.75%),weak AF in the macular edema area with weak or strong spot-like or plate-like AF scattered(11 eyes,13.75%).FFA fluorescein leaking point or abnormal fluorescence were in accordance with abnormal AF in 47 eyes of 45 patients(58.75%),not in accordance in 33 eyes of 31 patients(41.25%).The IR image of ocular fundus was in accordance with FFA fluorescein leaking point in 68 eyes of 65 patients(85.00%),not in accordance in 12 eyes of 11 patients(15.00%).CONCLUSION:IR and AF provide a novel,fast and non-surgical method for the diagnosis of CSC.IR and AF as complement are combined with FFA for the diagnosis of CSC.