·AIM:To investigate the impact of anxiety value on the vital sign of age-related macular degeneration(AMD)patients after lucentis treatmeant.METHODS:Thirty eyes of 30 patients with AMD were enrolled in the study.They were investigated in questionaire way and the results were compared with the average value of the whole country.The diversification of the rhythm of heart and blood pressure ten minutes before and after infection were measured.RESULTS:The scale of AMD patient was much higher than the average of the whole country.There was statistical significance between two groups(P<0.05).CONCLUSION:The AMD patients are anxiety and their vital signs are affected before treatment.