·AIM:To discuss two different surgical treatments and effects for pterygium.METHODS:The patients were divided into two groups.25 patients with pterygium surgical excision combined with mitomycin C treatment were in group A,10 patients treated with autologous conjunctival limbal stem cell transplantation and corneal limbal stem cell transplantation in group B.The corneal wound healing,conjunctival wound healing,and recurrence of pterygium were observed.RESULTS:In group A,the recovery of corneal epithelium occurred 3-7 days after surgery,conjunctival congestion was subsided 10-15 days after surgery,and 3 cases recurred.In group B,the recovery of corneal epithelium occurred 2 days after surgery,conjunctival congestion was subsided 7-10 days postoperatively,and 1 case was recurrent.CONCLUSION:Pterygium excision combined with mitomycin and autologous conjunctival limbal stem cell transplantation and corneal limbal stem cell transplantation can reduce the recurrence rate of pterygium.The conjunctival and corneal limbal stem cell transplantation is better compared with pterygium excision combined with mitomycin.