目的:探讨腹型肥胖与非动脉炎性前部缺血性视神经病变(non-arteritic anterior ischemic optic neuropathy,NAION)发生的相关性。方法:连续收集45例中国陕西籍或长期居住在北方地区的汉族NAION患者作为观察对象(即NAION组),并且无糖尿病、严重心脑血管疾病、肝肾功能不全等疾病;选择45例按年龄、性别、体质量指数条件与观察对象相匹配的健康查体者或其它眼病患者,自愿参与作为对照组。男性腰围≥85cm,女性腰围≥80cm,定义为腹型肥胖。结果:NAION组中腹型肥胖31例(69%)高于对照组21例(47%),两者比较有统计学差异(P<0.05);NAION组中吸烟者26例(58%),饮酒者20例(44%),对照组中吸烟者11例(24%),饮酒者16例(36%),吸烟方面两组间有统计学差异(P<0.05),而饮酒在两组间无统计学差异(P>0.05)。结论:中国北方汉族人群腹型肥胖与NAION发病有一定的关系。

AIM:To investigate the association of abdominal obesity with non-arteritic anterior ischemic optic neuropathy(NAION).METHODS:The cohort study was consisted of 45 individuals of Han nationality in Shaanxi or northern areas that had been diagnosed with NAION and 45 healthy controls [matched for age,gender and body mass index(BMI)].None of the cases or controls had a history of diabetes,serious cardio-cerebral vascular diseases,liver and kidney dysfunction.The waist circumference(male’s≥85cm,female’s≥80cm)was defined as abdominal obesity.RESULTS:It was found that 31(69%) of 45 NAION patients had abdominal obesity,but only 21(47%) of 45 controls had it,there was no significant difference between NAION patients and controls(P<0.05).There were 26 smokers(58%),20 drinkers(44%) in NAION group,11 smokers(24%),16 drinkers(36%) in the control group,there was statistically significant difference between the two groups in smoking(P<0.05),and there was no statistically significant difference between the two groups in drinking(P>0.05).CONCLUSION:Abdominal obesity may be associated with the susceptibility to NAION in the northern Chinese population of Han nationality.

R774.6