目的:比较鹰视酷眼和蔡司Mel80两种准分子激光机在矫正低、中度近视中的角膜切削厚度。方法:前瞻性对照研究。将近视患者58例108眼分为两组,其中31例55眼接受鹰视酷眼激光机行准分子激光原位角膜磨镶术(laser in situ keratomileusis,LASIK)治疗为A组,组内等效球镜在-0.50～-3.00D范围内为A1组(25眼),-3.25～-6.00D范围内为A2组(30眼)。27例53眼接受蔡司Mel80激光机治疗为B组,同法分为B1组(23眼)和B2组(30眼)。手术均采用小光斑随机飞点扫描Q值优化非球面切削模式,术中使用Moria2自动旋切式角膜板层刀制作角膜瓣,对治疗区直径及光学区等参数统一设定。术前及术后1mo行角膜厚度检查,其差值为角膜切削厚度实际值。分别比较A1和B1组间、A2和B2组间角膜切削厚度。统计学方法采用多个独立样本均数采用单因素方差分析。结果:A1,A2组角膜切削厚度的实际值与理论值比较,差别均无统计学意义(P=0.081,0.444)。B1,B2组角膜切削厚度的实际值低于理论值(P=0.000,0.000)。角膜切削厚度理论值A1组低于B1组(P=0.001),A2组低于B2组(P=0.000)。实际值A1与B1,A2与B2组差别无统计学意义(P=0.832,0.884)。结论:酷眼和Mel80准分子激光机的实际角膜切削厚度无差别。酷眼机的理论值与实际值一致,可用于准确预测切削量,Mel80机的理论值显著高于实际值。

AIM:To compare Wavelight Allgegrotto Wave Eye-Q and Zeiss Meditec MEL 80 Excimer Lasers about corneal ablation depth after customized aspheric ablation to correct mild and moderate myopia.METHODS:Prospective comparative study.58 cases(108 eyes) with myopia were randomly divided into two groups.31 cases(55 eyes) in group A were treated by Lasik with Wavelight Allgegrotto Wave Eye-Qand the other 27 cases(53 eyes) in group B were treated by Meditec Mel 80.The patients in group A were divided into group A1 and A2 according to the shortsighted degree,representing mild and moderate subsets respectively.The patients in group B were divided into group B1 and B2 as well.Both excimer lasers applied Q-index optimized ablation profile.Moria M2 Automatic Microkeratome was used to operate corneal flap.Treatment zone diameter and optical zone diameter were uniform in all cases.Corneal thickness were measured before and 1 month after surgery.Multiple independent sample mean used single-factor analysis of variance statistically.RESULTS:The actual corneal ablation depth and the theoretical corneal ablation depth didn’t differ significantly in A1 and A2(P=0.081,0.444).The actual corneal ablation depth was less significantly than theoretical corneal ablation depth in B1 and B2(P=0.000,0.000).The theoretical corneal ablation depth in group A1 was significantly less than that in group B1(P=0.001) and similar in moderate subset groups(P=0.000).Actual corneal ablation depth was no different between group A1 and B1(P=0.832)and similar in moderate subset groups(P=0.884).CONCLUSION:Wavelight Allegretto Wave Eye-Q and Mel 80 excimers laser have similar actual corneal ablation depth.Theoretical corneal ablation depth in group A has no difference from the actual one and can be used to predict postoperative corneal thickness exactly.Theoretical corneal ablation depth in group B is much more than the actual one.

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