AIM:To observe early synthetic methods for treatment of ocular thermal burns by hot metal liquid.METHODS:Fifty-six eyes (52 cases) received removement of metal remnant and conjunctival injection of idios blood serum at once.The gelatin sponge absorbed with recombinant bovine basic fibroblast growth factor eye-gel,lomefloxacin eye-gel,and atropine eye onintment,were put into the conjunctival sac and corneal surface.The gelatin sponge were changed every 3 days.The intravenous antibiotic,glucocorticoid and xuesaitong were used to control infection and inflammation and to promote nutrition.On 6th day after injury we stopped using glucocorticoid.Amniotic membrane transplantation was used for the case with the risk of corneal perforation.RESULTS:The eyeballs were all saved in 56 eyes,and nebula in 17 eyes,macula in 9 eyes,leucoma in 7 eyes,pseudo-pterygium in 18 eyes,entropion in 11 eyes,ectropion in 1 eye,symblepharon in 2 eyes.CONCLUSION:Early synthetic therapy for ocular thermal burns by hot metal liquid can promote eye conditions,prevent or reduce complications,and create a good condition for surgery.