AIM:To investigate the clininal effect of limbal stem cell autograft transplantation with bulbar conjunctival flap in the pterygium.METHODS:Totally 96 patients 112 eyes with pterygium were treated by limbal stem cell autograft transplantation with bulbar conjunctival flap.Postoperative reaction,graft vitality and recurrence of pterygium were observed.RESULTS:All cases were found with transient reaction,the grafts grew well without serious complication and no recurrence was found during the follow-up of 6-12 months.CONCLUSION:Limbal stem cell autograft transplantion with bulbar conjunctival flap is effective and safe for treatment of pterygium.It is good-looking on the ocular surface and recurence rate is lower,which is a method worth popularizing.