AIM:To study the formation and treatment characteristics of amblyopia in children. METHODS:Retrospective analysis was done on the clinical data of treatment of 176 cases (291 eyes) of amblyopia in children. RESULTS:All 176 cases of amblyopia in children, mild amblyopia was in 19 cases, moderate 81 cases, severe 76 cases; refractive error accounted for 68.75%, strabismus accounted for 14.21%, anisometropia accounted for 11.93%, the form deprivation and congenital amblyopia accounted for 3.41% and 1.70%; total cure rate was 70.80%. CONCLUSION: Most amblyopia in children are functional, efficacy is closely related to children age, the type and degree of amblyopia.Comprehensive therapy focused on the gradual elimination of macular functional inhibition of amblyopia eye, which is the the best measurement for the treatment of amblyopia in children.