AIM:To observe the clinical effect of propranolol for ocular hemangioma. METHODS:Totally 52 cases of children of ocular hemangioma were divided into the treatment group of 31 cases and control group of 21 cases.The treatment group was treated with oral propranolol for eyelid hemangioma,the control group was treated with oral prednisone acetate. RESULTS:Improvement rate was 100% in treatment group, and 81% in control group.General-cure rate was 81% in treatment group,and 43% in control group.Cure rate was 26% in treatment group, and 10% in control group.The total effective rate was 100% in treatment group, and 81% in control group (P<0.01). CONCLUSION:Oral propranolol for ocular hemangioma treatment has remarkable curative effect.It is worth clinical application.