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[摘要]
研究外伤性眼内炎的病原及玻璃体切割术联合玻璃体腔注药治疗外伤性眼内炎的临床疗效分析。 方法:对临床病历资料完整的36例行玻璃体切割联合玻璃体腔注药治疗外伤性眼内炎患者资料进行整理分析,比较患者术前术后视力,分析受伤原因及病原体培养结果。 结果:随访5~36mo,行玻璃体切割联合玻璃体腔注药的36例患者术后感染均得到有效控制,24例患者视力有不同程度提高,占67%。球内异物是最主要的致病原因。22例术中取玻璃体行微生物学检查,7例检查阳性,其中革兰氏阳性球菌3例,革兰氏阴性杆菌1例,真菌2例,混合感染1例。 结论:玻璃体切割联合玻璃体腔注药是治疗外伤性眼内炎的有效方法,玻璃体腔内注入有效药物是提高外伤性眼内炎治愈率的关键
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[Abstract]
-To compare the effect of the treatment on viral optic neuritis in a comprehensive therapy of Ganciclovir combined methylprednisolone and comprehensive therapy of methylprednisolone. METHODS:Fourty-one cases 41 patients (60 eyes) with viral optic neuritis were randomly divided into a control group with 20 cases (30 eyes) and a treatment group with 21 cases (30 eyes). Visual acuity and visual evoked potential (VEP)were observed on patients before treatment and on 3rd, 7th, 14th,30th,90th,180th day after treatment . RESULTS:Visual acuity and LP100 in two groups were improved over time (P<0.01). Visual recovery had begun on 3rd day after treatment, visual acuity in the treatment group was better than that in the control group after 1 month (P=0.009), no difference was between the two groups in improved visual acuity after 6 months (P>0.05); the trend that LP100 in both groups was improved with time (P<0.01)was showed, a fast recovery rate was showed for LP100 in both groups in treatment early (within 2 weeks)stage, the difference was significant compared with pretreatment (P<0.01). However, the recent recovery effect on LP100 in the treatment group was better than that in the control group and a little difference was showed in the late treatment stage. CONCLUSION:Visual acuity and LP100 can be more quickly improved and the optic nerve electrical activity be strengthened in the comprehensive therapy of Ganciclovir combined methylprednisolone to treat viral optic neuritis compared with the comprehensive therapy of methylprednisolone so as to improve the visual quality of patients.
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