AIM:To evaluate the clinical effects of Nd:YAG laser combined with novel lacrimal duct stent implantation treatment for nasolacrimal duct obstruction． METHODS:Totally 26 cases (29 eyes)with nasolacrimal duct obstruction were implanted with lacrimal duct stents after Nd:YAG laser surgery, and irrigated lacrimal duct regularly after surgery. RESULTS:All cases were followed up for 9-12 months.22 eyes were cured， 5 eyes improved，and 2 eyes(7%) treated ineffectively．The total efficiency was 93％. CONCLUSION:The novel lacrimal duct stent and the operation procedure are safe and simple,with less tissue hurt.It is an effective method for treating lacrimal duct obstruction and chronic dacryocystitis.