AIM: To observe the early postoperative intraocular pressure(IOP)of transplantation of autologous retinal pigment epithelium(RPE)-Bruch membrane complex after the removal of corneal neovascularization(CNV).

METHODS: A retrospective study was performed in 24 patients 25 eyes with age-related macular degeneration(ARMD)who underwent vitreoretinal surgery and related literatures were reviewed. The 24 patients 25 eyes were divided to group A(the macular subretinal hemorrhage and CNV removal surgery group, n=14)and group B(transplantation of autologous RPE-Bruch membrane complex after the removal of the CNV group, n=11). IOP was measured before surgery and then on day 1, 2, 3, 4, 5, 6 and 7 after surgery with Goldmann applanation tonometer. Two sets of IOP were counted and possible factors were analyzed for association with ocular hypertension.

RESULTS: The IOP was elevated on day 1 after surgery in 78.1% of all cases, and also elevated significantly on day 2 in 56.4% of group B, respectively. Besides, the mean postoperative IOP, the peak postoperative IOP and incidence of high IOP at week 1 was elevated significantly in group B, respectively.

CONCLUSION: Early postoperative IOP and incidence of high IOP in patients with hemorrhagic ARMD undergoing transplantation of autologous RPE-Bruch membrane complex after the removal of the CNV have significant elevation, and need for perioperative prevention of high IOP should be noted.