AIM: To investigate the application of pranoprofen eyedrops in laser epithelial keratomileusis(LASEK).

METHODS:Totally 112 eyes of 56 patients who have undergone LASEK in our hospital from May 2011 to August 2011 were divided into experimental group(use of pranoprofen)and control group. Corneal irritation and healing of epithelium between these two groups were compared and observed.

RESULTS: Corneal irritation in the study group was much better than that of the control group on 1-day and 3-day after operation. However, there was no obvious difference in the healing of the epithelium.

CONCLUSION:Pranoprofen eyedrops can significantly alleviate corneal irritation after LASEK, and will not affect the healing of epithelium, nor increase the ratio of secondary ocular hypertension.