AIM: To discuss the treatment plan for glaucoma with congenital microphthalmos.

METHODS: Clinical data and treatment plans of 10 cases affected with congenital microphthalmos(20 eyes)accepted from 1998 to 2011 at ophthalmology department of Xiaogan Central Hospital were reviewed. Follow-up visit lasted 6-47 months.

RESULTS: All the 10 patients(20 eyes)were affected with medium and hyperpresbyopia as well as shallow anterior chamber, 14 eyes suffered closure glaucoma. After preliminary diagnosis, 5 eyes were detected with eye pressure between 22-40mmHg, 9 eyes with eye pressure>40mmHg. 8 eyes therein underwent trabeculectomy. 3 eyes were found with post-operational eye pressure ≤21mmHg, 3 eye with eye pressure between 21-30mmHg, and 2 eyes affected with malicious glaucoma. 6 eyes were treated by ultrasonic phacoemulsification and then trabeculectomy 3 months later. Then 4 eyes were detected with eye pressure ≤21mmHg and with eye pressure between 21-30mmHg. No malicious glaucoma was detected.

CONCLUSION: For closure glaucoma with congenital microphthalmos, treatment only with glaucoma filtration surgery may easily result in failures because of malicious glaucoma and incontrollable eye pressure. To perform cataract extraction in advance will conduces to risk reduction of malicious glaucoma and enhancement of the surgery successful rate.