AIM: To find and determine the environmental factors causing the dry eye syndrome, and to provide the etiology basis for the prevention and treatment of dry eye.

METHODS: Totally 233 subjects were chosen out of routine physical examining persons in our hospital from September 2011 to September 2012. There was no eye disease of anterior segment. It mainly included two parts-questionnaires and tear function tests. Questionnaire content included working environment, smoking status, occupation, the phosphor screen contact time, driving time, and air-conditioned room residence time. First, single-factor analysis was performed to identify the environmental factors associated with dry eye incidence, then the meaningful factors with multifactor comprehensive analysis was made to identify and determine the major risk factors leading to dry eye.

RESULTS:Univariate analysis showed that environmental factors associated with dry eye incidence were phosphor screen contact time, work environment, smoking status, driving time, and air-conditioned room residence time. Logistic regression analysis showed that the significant factors were the phosphor screen contact time, work environment, smoking status, driving time.

CONCLUSION:In terms of the factors included in this study, the main environmental factors impacting dry eye disease is phosphor screen contact time, the work environment, smoking status, driving time.