AIM:To explore possible causes of early postoperative elevated intraocular pressure caused by proliferative diabetic retinopathy(PDR)vitrectomy.

METHODS:Totally 72 cases(100 eyes)which have performed vitrectomy for proliferative diabetic retinopathy were retrospectively analyzed to observe the incidence of postoperative ocular hypertension, and the relevant factors that caused postoperative high intraocular pressure were statistically analyzed. Early postoperative ocular hypertension diagnostic criteria: any time after 2 weeks of non-contact tonometer measured IOP> 25mmHg(1mmHg=0.133kPa).

RESULTS:High intraocular pressure after vitrectomy occurred in 27 eyes(27%), the incidence of male and female were 27.27%, 26.79%, the difference was not statistically significant(P>0.05). Eyes filled with balanced liquid filling incidence rate of 30.95%, 6.25%, and the difference was statistically significant(P<0.05). Silicone oil tamponade with C3F8 filled group incidence rate of 34.28%, 31.25%, and the difference was not statistically significant(P>0.05). Incidences of intraoperative panretinal photocoagulation and additional retinal photocoagulation group were 41%, 20%, and the difference was statistically significant(P<0.05). Preoperative retinopathy of four, five, six groups of incidence were 9.52%, 23.81%, 40.56%, and the groups were statistically significant(P<0.05). Unconsolidated preoperative retinal detachment and retinal detachment incidence rate of 19%, 41%, and the difference was statistically significant(P<0.05). Surgery in the united lens resection with intraoperative unfederated lens the resection group's incidence rate of 34%, 15%, the difference was statistically significant(P<0.05). Logistic regression analysis showed that retinal detachment preoperative and intraoperative intraocular filling were independent risk factors that caused early postoperative ocular hypertension after vitrectomy.

CONCLUSION:Post-operative ocular hypertension after PDR vitrectomy is related to preoperative retinal detachment, intraoperative lensectomy, intraoperative intraocular filling, and intraoperative panretinal photocoagulation. Retinal detachment preoperative and intraoperative intraocular filling are independent risk factors that caused early postoperative ocular hypertension after vitrectomy. Incidence of postoperative ocular hypertension after PDR vitrectomy is high, harmful. Early detection and individualized treatment can improve the success rate of vitrectomy and the patient's vision.