AIM: To observe the safety and clinical effects of Cachet IOL implantation in the correction of high myopia.

METHODS: Twelve high myopia patients with Cachet anterior chamber IOL implantation from May 2011 to December 2011 were recruited in clinical study. The change of vision, IOP, corneal endothelium and the complication were observed after therapy. The follow up time was 3-6 months.

RESULTS: In all eyes of 12 patients, the uncorrected distance visual acuity(UDVA)and corrected distance visual acuity(CDVA)were obviously improved in different degrees after surgery compared with those of pre-therapy. The anterior chamber was clear at 2 days after therapy. The loss rate of corneal endothelium was low, the IOL of all patients had a good position and there were no obvious complication after therapy.

CONCLUSION: The Cachet IOL implantation is an accurate method in the correction of high myopia. It is an effective therapy to lighten the response of anterior chamber, and remission of complication and improve the vision. However, its safety needs long time observation.