Abstract:AIM: To observe the effects and complications of treatment foruveitis with cystoid macular edema with two different dosages of intravitreal triamcinolone acetonide(IVTA).
METHODS: Totally 6 cases(12 eyes)suffering from bilateraluveitis with cystoid macular edema were selected for the study from January 2010 to January 2012 treated in our hospital. Two eyes of each patient was divided into two groups randomly. Group A was treated with IVTA 4mg, group B was treated with IVTA 2mg. The visual acuity, intraocular pressure, foveal thickness, transparency of lens and recurrence of uveitis etc were examined postoperatively. The data were analyzed by t test.
RESULTS: The visual acuity of all patients was improved obviously after operations. A relief ofcystoid macular edema was observed in 12 eyes(100%)after operations, which was a significant difference contrast with preoperation(P<0.01). Preoperative and postoperative mean thickness of foveal in group A and group B had no difference(P>0.05). Three cases(3 eyes)in each group(50%)occurred high intraocular pressure. The mean intraocular pressure controlled with drugs of group A was 44.33±7.51mmHg, and group B was 23.33±2.52mmHg, which was significantly different(P=0.01)between two groups. Four eyes of 2 patients manifested cataract in each group. Four eyes of 2 patients underwent recurrent uveitis with cystoid macular edema after the treatment.
CONCLUSION: IVTA is an effective treatment foruveitis with cystoid macular edema. Complications include high intraocular pressure and progression of cataract. Therapeutic efficiency was the same of IVTA in two different dosages in treating uveitis with cystoid macular edema, but complication of high intraocular pressure was lower in IVTA 2mg than that of IVTA 4mg.