AIM: To discuss the meaning of measuring gradient AC/A ratio in preventing and correcting adolescent myopia.

METHODS: Sixty subjects(30 early-onsetmyopes, 10 late-onset myopes and 10 emmetropes)participated in this study. The stimulant accommodative gradient AC/A ratio were measured.

RESULTS: There was a significant difference in the response AC/A between early-onsetmyopes, late-onset myopes and emmetropes(t=2.84, P<0.01 and t=2.71, P<0.01,respectively).

CONCLUSION: Early-onset myopia has a higher response AC/A than late-onset myopia andemmetropia, which suggest that higher AC/A may be the risk factors for myopia onset and progression.