AIM: To observe the outcome of application of water sac under the conjunctival flap formation combing with adjustable suture in estimating and controlling the post-operational filtering outflow in compound trabeculectomy.

METHODS: Totally 200 eyes of 186 cases of primary glaucoma were randomly divided into observation group and compared group. All eyes of observation group underwent application of water sac under the conjunctival flap formation combining with ajdustable suture and mitomycin-C in compound trabeculectomy. Eyes in control group underwent compound trabeculectomy only. All cases were observed for 12 months, including visual acuity, intraocular pressure(IOP), filtering blebs, depth of anterior chamber, and other complications.

RESULTS: In the early term after operation, the shallow anterior chamber and other complication in observation group was obviously less than that in control group. In the far term after operation, the IOP in observation group was lower than that in control group, visual loss and non functional blebs in observation group was obviously less than that in control group.

CONCLUSION: Water sac under the conjunctival flap formation combining with adjustable suture in compound trabeculectomy is useful for controlling IOP, and less complication(bleb leakage, shallow anterior chamber, malignant glaucoma etc.)