AIM: To compare the clinical effect of phacoemulsification cataract extraction and intraocular lens implantation combined with trabeculectomy, and goniosynechialysis in the treatment of cataract and angle-closure glaucoma. The results provided a reliable method for the treatment of cataract patients with angle-closure glaucoma.

METHODS: Seventy-eight patients(106 eyes)with cataract and angle-closure glaucoma were randomly divided into two groups. Group A contained 40 patients(56 eyes)which were treated by using phacoemulsification cataract extraction and intraocular lens implantation combined with trabeculectomy. Group B included 38 patients(50 eyes)which were treated with phacoemulsification cataract extraction and intraocular lens implantation combined with goniosynechialysis. The clinical effect was compared between the two groups. The following clinical parameters were tested before and after treatment: visual acuity, intraocular pressure, anterior chamber depth, and incidence of complications.

RESULTS: The operations of the two groups were all smooth. There was significant difference between before and after treatment concerning visual acuity, intraocular pressure, anterior chamber depth, angle changes(P<0.05). Comparison of the efficacy of the two groups after operations: 49 eyes angle completely open in group A, 44 eyes angle completely open in group B. No significant statistical difference was found between the two groups. Preoperative anterior chamber depth: group A was 1.73±0.42mm and group B was 1.78±0.39mm; anterior chamber depth after operation: group A was 3.25±0.36mm, group B was 2.91±0.53mm. There was significant difference between the two groups. Occurrence of complications in group A was significantly higher than that of group B.

CONCLUSION: Phacoemulsification cataract extraction and intraocular lens implantation combined with goniosynechialysis in the treatment of cataract patients with angle-closure glaucoma can significantly improve visual acuity, effectively control intraocular pressure, and reduce early complications of operation. The method of operation is simple, and can be widely used.