AIM: To evaluate the effects of sanxuemingmu capsule combined with compound anisoine in the ocular ischemic disease.

METHODS: We divided our patient into two groups according to their blood-activating and stasis-dissolving drug using history at first, then divided them into observation/positive/negative control subgroups according to random case-control method. The clinical key data and advert effects after 3 cycles of treatment were obtained by visual acuity/visual field and color Doppler.

RESULTS: The index of general effects/visual acuity/the general visual acuity loss/the artery/vein perfusion time of fundus fluorescein angiography(FFA)and color Doppler index(CDI)together with the advert effects rate of cardiovascular system of the observation groups were significantly better than those of the contrast groups.

CONCLUSION: The combination of sanxuemingmu capsule with anisoine is effective in the ocular ischemic diseases and can lessen the cardiovascular advert effect rate of ocular ischemic diseases suffer while this administration method is more benefit in cases without blood-activating and stasis-dissolving drug using history than cases with drug using cases.