AIM:To investigate the biometric properties of the anterior segment in myopic anisometropia, and to determine their role and variation tendency in the development of myopia.

METHODS: Seventy–nine patients with myopic anisometropia(spherical equivalence difference ≥1.00D)were recruited for the study. According to the diopters of spherical equivalence(SE), the eyes were divided into three groups: Group A(SE≥-3.00D), Group B(-6.00Dt-test was used to evaluate the interocular differences in the parameters of each patient. One-way ANOVA was used to evaluate the difference of parameters between groups.

RESULTS: There was no significant interocular difference in any parameters(P>0.05). The interocular difference of corneal spherical aberration had no correlation with the SE(r_right=-0.013, P_right=0.909; r_left=0.053, P_left =0.641). There were no significant differences in any parameters between Group A, B, C or between Group A', B', C'(P>0.05).

CONCLUSION: Myopic anisometropic eyes display a high degree of interocular symmetry for a range of anterior eye biometric and optical parameters, indicating that the interocular refraction difference is not caused by anterior segment biometrics or corneal aberrations.