AIM: To observe the combined effect of Sodium hyaluronate eye drops and recombinant bovine basic fibroblast growth factor(bFGF)eye drops on cornea epithelial repair after corneal rust foreign body extraction.

METHODS: Alinety-eight cases(98 eyes)of corneal rust foreign body patients were randomly distributed to combined treatment group(49 cases, 49 eyes)and control group(49 cases, 49 eyes). Hyaluronate eye drops, recombinant bFGF eye drops and levofloxacin hydrochloride were applied in combined treatment group after corneal foreign body extraction. Recombinant bFGF eye drops and levofloxacin hydrochloride were applied in control group. Corneal fluorescein stain, cornea epithelial repair and local symptoms were examined thrice weekly for 2 weeks.

RESULTS: General effective rate of treatment in combined group reach 96%, significantly higher than that in control group(88%, P<0.05).

CONCLUSION: Combined application of sodium hyaluronate eye drops and recombinant bFGF eye drops can prominently improve cornea epithelial repair after corneal lesion with proven effectiveness and safety.