AIM:To observe the clinical effect of vitrectomy for proliferative diabetic retinopathy(PDR).

METHODS: The clinical data of 55 cases(65 eyes), underwent vitrectomy, membrane peeling, endolaser photocoagulation and silicone oil or C₃F₈ injection, were retrospectively studied. During 6 months to 1 year follow-up period, visual acuity, intraocular pressure, retinal conditions and complications were observed.

RESULTS: All 65 eyes received vitrectomy, of which silicone oil was tamponaded in 32 eyes, C₃F₈ was injected in 8 eyes, BBS was filled in 25 eyes. Visual improvement achieved in 42 eyes. Two eyes were manually vision, form count fingers to 0.05 in 18 eyes, >0.05-0.1 in 28 eyes, >0.1-0.3 in 12 eyes and >0.3 in 5 eyes. Retinal hole was occurred in 7 eyes, limitations fibrosis membrane remained in 8 eyes, retinal detachment appeared in 5 eyes, IOP increased in 18 eyes, vitreous hemorrhage relapsed in 12 eyes, 36 eyes received supplemental photocoagulation treatment 1-3 times after operation.

CONCLUSION:Vitrectomy combined endophotocoagulation is an effective treatment for PDR. Silicone oil tamponade can limit the hemorrhage.