AIM: To evaluate the effect of Qinpi eye drops combined with Cyclosporin A eye drops in the treatment of dry eye syndrome.

METHODS: Totally, 200 patients(400 eyes)with dry eye syndrome were randomly divided into experiment group and control group, 100 cases(200 eyes)for each. The experiment group was treated by Qinpi eye drops combined with Cyclosporin A eye drops four times per day. The control group was treated by 0.5g/L Cyclosporin A eye drops every 30min only four times per day(one drop per time, 1mL≈15 drops). The Schirmer test(SⅠt), tear film break up time(BUT)were compared with before and after 4 weeks' therapy in both groups. The results were analyzed statistically.

RESULTS: There were significant differences in SⅠt and BUT 4 weeks later after treatment in both groups(P<0.01)whereas no difference before the treatment(P>0.05). There were significant differences in SⅠt and BUT in experiment group compared with control group after 4 weeks(P<0.01).

CONCLUSION: Qinpi eye drops combined with Cyclosporin A eye drops is an effective method for dry eye syndrome.