AIM: With the advancement of pars plana vitrectomy, especially the intraocular application of inert gases and silicone oil, many serious vitreoretinal diseases, such as vitreous hemorrhage, endophthalmitis, proliferative diabetic retinopathy etc. have received effective treatment. But it is undeniable that there are many complications after vitrectomy that have seriously affected patients' vision recovery. The aim of this study is to observe the incidence and pathogenesis of various complications after vitrectomy to provide some clinical references to avoid and reduce the incidence of complications.

METHODS: This paper retrospectively analyzed records of 200 cases that underwent vitrectomy operated by the same surgeon. Inert gasesor silicone oil was filled accordingly. According to filling agent, patients were divided into simple vitrectomy group, inert-gas tamponade group and silicon-oil tamponade group; according to ocular hypertension onset, patients were divided into normal intraocular pressure group and ocular hypertension group; according to age, patients were divided into ≥50 group and <50 group. Relative analysis was made on the incidence, dangerous factors and management of complications in each group after vitrectomy.

RESULTS: According to the study, the major postoperative complications of vitrectomy were increase of introculr tension, secondary glaucoma, corneal diseases, complicated cataract, vitreous hemorrhage, retinal detachment, iatrogenic retinal hole, fibrin formation in anterior chamber, choroid and ciliary body detachment, and so on. According to statistical analysis of data of this group, it was believed that there were obvious differences among simple vitrectomy group, inert-gas tamponade group, silicon-oil tamponade group in postoperative complications. The postoperative incidence of increase of introculr tension and secondary glaucoma in inert-gas tamponade group and silicon-oil tamponade group were obviously higher than that in simple vitrectomy group. What's more, in inert-gas tamponade group, the postoperative incidence of ocular hypertension was much higher. The postoperative incidence of corneal complications and complicated cataract in inert-gas tamponade group and silicon-oil tamponade group were obviously higher than that in simple vitrectomy group and closely correlated with postoperative ocular hypertension. There were no distinct differences among every group in vitreous hemorrhage, iatrogenic retinal hole and retinal detachment, fibrin formation in anterior chamber, choroid and ciliary body detachment.

CONCLUSION:Vitrectomy is an important and effective treatment method for serious vitreoretinal diseases and most patients have obtained different visual improvement after the surgery. But postoperative complications seriously affect postoperative effect. The key to the success of vitreous retinal surgery in the future is that how to improve surgical techniques to avoid, reduce and timely dispose postoperative complications. It is also the emphasis of research of vitrectomy which deserves more exploration and research.