方法：近视患者102例204眼，平均屈光度-3.36±1.07D(等效球镜)，用临床问诊、视力检查、裂隙灯检查等方式， 观察戴镜2a平均屈光度、裸眼视力、眼轴、中央角膜厚度、视觉异常(有无复视、眩光、重影)以及眼表并发症等情况。

结果：戴镜6mo； 1，2a与戴镜前相比，裸眼远视力、平均屈光度变化有显著差异(P<0.05)，所有患者配戴镜片后屈光度降低，视力改善； 眼轴、中央角膜厚度戴镜前后差异无显著变化(P>0.05)，角膜健康状况良好，因戴镜所致不适症状经适当用药或镜片处理后均可消失。

结论：角膜塑形镜是一种有效地矫正视力和控制近视增长的方法。在使用合格的产品、规范的流程、合格的验配技术和严格的复查的前提保障下长期配戴角膜塑形镜是安全的。

METHODS: There were 204 eyes of 102 myopic patients, whose average diopter was -3.36±1.07D(spherical equivalent). The changes of mean myopia diopter, uncorrected visual acuity(UCVA), axial length, corneal thickness, visual quality and complications during two years of receiving orthokeratology treatment by the way of clinical diagnosis, general examination, slit lamp examination and corneal thickness examination were observed.

RESULTS: After receiving orthokeratology treatment for half a year, one year and two years, the naked vision and the mean myopia diopter had significant difference(P<0.05), the mean myopia diopter of all patients were decreased, and their naked vision were improve. There was no significant difference in corneal thickness and axial length(P>0.05). The corneal of patients were in good health. Discomfort symptoms due to wearing glasses can disappear after reasonable medication and adjustments with the glasses lenses.

CONCLUSION: Orthokeratology is a kind of method of effectively correcting eyesight and controlling growth of myopia. In the premise of security products, standard processes, qualified fitting technology and rigorous review, Long-term wearing orthokeratology lens is safe.